Role of apoptosis-inducing factor in perinatal hypoxic-ischemic brain injury
نویسندگان
چکیده
منابع مشابه
Neuroprotective effects of geneticin (G418) via apoptosis in perinatal hypoxic-ischemic brain injury
접수 : 2007년 12월 4일, 승인 : 2008년 1월 9일 이 연구는 2002년도 대구가톨릭대학교 의과학연구소 연구비의 지원으로 이루어졌음 책임저자 : 김우택, 대구가톨릭대학병원 소아과청소년과 Correspondence : Woo Taek Kim, M.D. Tel : 053)650-4250 Fax : 053)622-4240 E-mail : [email protected] xia at birth is estimates to be 0.2-0.4% in full-term newborn infants and approaches 60% in preterm infants. About 20-50% of infants suffering from H-I encephalopathy expire during the ...
متن کاملPharmacological Neuroprotection after Perinatal Hypoxic-Ischemic Brain Injury
Perinatal hypoxia-ischemia (HI) is an important cause of neonatal brain injury. Recent progress in the search for neuroprotective compounds has provided us with several promising drugs to reduce perinatal HI-induced brain injury. In the early stage (first 6 hours after birth) therapies are concentrated on prevention of the production of reactive oxygen species or free radicals (xanthine-oxidase...
متن کاملNeuroprotective Therapies after Perinatal Hypoxic-Ischemic Brain Injury
Hypoxic-ischemic (HI) brain injury is one of the main causes of disabilities in term-born infants. It is the result of a deprivation of oxygen and glucose in the neural tissue. As one of the most important causes of brain damage in the newborn period, the neonatal HI event is a devastating condition that can lead to long-term neurological deficits or even death. The pattern of this injury occur...
متن کاملThe role of oxidative stress in perinatal hypoxic-ischemic brain injury.
INTRODUCTION The pathogenesis of perinatal hypoxic-ischemic brain damage is highly complex. OBJECTIVE The aim of this study was to assess the role of oxidative stress in hypoxic-ischemic brain injury and subsequent abnormal neurological outcome in infants with perinatal hypoxic-ischemic encephalopathy (HIE). We estimated perinatal oxidative brain damage measuring activity of glutathione perox...
متن کاملRole of immunoglobulin in neuronal apoptosis in a neonatal rat model of hypoxic ischemic brain injury
The objective of the present study was to evaluate the neuroprotective effects of immunoglobulin (Ig) in a neonatal hypoxic ischemic (HI) rat model. Seven-day-old rat pups were randomly assigned to control, hypoxia and hypoxia + Ig groups. The rats in the hypoxia +Ig group were intraperitoneally administered 1 g/kg Ig once, immediately after hypoxia. Saline was administered to the rats in the h...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2021
ISSN: 1673-5374
DOI: 10.4103/1673-5374.290875